Anti-inflammatory peptides
BPC-157
Modulates nitric oxide, anti-TNF effects in gut and systemic models. Strong evidence in rodent gut inflammation models.
KPV (Lys-Pro-Val)
Tripeptide derived from alpha-MSH. NF-κB inhibition, reduced IL-6. Studied for IBD.
Thymosin Beta-4 / TB-500
Reduces TNF-α and other inflammatory cytokines. Anti-inflammatory in cardiac repair models.
LL-37 Cathelicidin
Innate immunity peptide. Anti-inflammatory in some contexts, pro-inflammatory in others (context-dependent).
Selank
Immunomodulatory peptide. Reduces inflammation in stress-related models.
Mechanism categories
- NF-κB inhibition (KPV)
- Cytokine modulation (BPC-157, TB-500)
- Nitric oxide system (BPC-157)
- Innate immunity (LL-37, thymic peptides)
Which is best for general inflammation?
BPC-157 has broadest evidence base.