BPC-157 |
BonesFocusHealingImmune systemPain |
- Wound healing, soft tissue injury recovery, reduce inflammation
- Bone, joint, tendons and ligaments health
- GI health (helps with gastric ulcers)
- Normalizing blood pressure
- Strengthens the immune system
- Positively impacts mood, behavior, and cognitive health
- Exhibits potential anti-cancer properties
- Stimulates formation of new blood vessels
- Helps with the scar tissue formation
|
- Treatment length: Not for long term 30 days
- SQ: 300 mcg daily (CCMT)
- IM: 150 mcg twice a day at the location of pain/injury
|
4 hours |
GHK-Cu, TB-500, Thymosin Beta-4 |
|
BPC stands for Body Protective Compound |
- Changes in blood pressure
- Changes in heart rhythm
- Dizziness
- Fatigue
- Hot flashes
- Nausea and vomiting
- Can affect mood if taking with SSRI
- Discontinue if causes depression or anxiety symptoms
|
CJC-1295 |
BonesCognitive functionEnergyHealingImmune systemLongevityMusclesSleep |
- Increases muscle mass and strength
- Improves bone density
- Increases lean mass
- Increases overall energy and well-being
- Used for burns or significant soft-tissue injury, post surgery
- Improves sleep quality
- Improves cognitive function
|
- Treatment length: 30 days
- Wait 2-3 hours after eating, and don’t eat for another 30 minutes after injection
- CJC-1295 DAC: SQ 100 mcg twice a week (SD)
- CJC-1295 no DAC: SQ 200 mcg nightly (5 nights on, 2 nights off) (CCMT)
- CJC-1295 no DAC is often stacked with Ipamorelin: SQ 200 mcg/200 mcg nightly (5 nights on, 2 nights off)
|
- CJC-1295 no DAC: 30 minutes
- CJC-1295 DAC: 6-8 days
|
Ipamorelin |
Tesamorelin |
- Also known as MOD GRF (1-29)
- Human growth hormone-releasing hormone (GHRH). GHRH should be paired with CHRP, as it increases the GHRP effect and you can use a lower dose
- CJC-1295 no DAC has shorter half-life, so more frequent injections are needed
- CJC-1295 DAC has longer half-life, so fewer injections are needed
|
- Water retention
- Tingling
- Numbness and decreased insulin sensitivity
- Tiredness, feeling of lethargy
- Head rush or euphoria
- Itching
|
Epitalon (Epithalon, Epithalamin) |
Immune systemLongevity |
- Slows down aging
- Suppresses tumor development
- Stimulates melatonin production, helping to regulate sleep cycles
- Prevents cardiovascular disease
- Boosts brain health
- Improves eye health
- Boosts immunity
- Treats symptoms of diabetes
|
- Note: There was a mistranslation between Epithalon and Epithalamin. Epithalamin is an extract of Epithalon and is less concentrated. The original studies in Russia and Ukraine actually used Epithalamin, that is why the dose is 10 mg. The equal Epithalon dose is 100 mcg.
- The protocols below are adjusted accordingly. 10 mg of Epithalamin = 100 mcg of Epithalon.
- IM or SQ: 100 mcg every 3 days for 15 days
- Epithalon is often stacked with Thymalin: IM (some do SQ): 5 mg thymalin and 5 mg epithalamine daily for 20 days, repeating every 6 months
|
Approximately 2.5 - 3 hours |
Thymalin (Epithalon is often stacked with Thymalin, enhancing immune and anti-aging effects) |
|
- There exists a mistranslation between Epithalon and Epithalamin
- Epithalamin is an extract of Epithalon and is less concentrated, so need to take 100 mcg of Epithalon instead of 10 mg of Epithalamin
- Similar translation issue exists for Thymogen and Thymalin
- Long-term results, but they may start showing up after the course is already done
|
- Diarrhea
- Difficulty sleeping
- Fatigue
- Flu-like symptoms
- Headache
- Irregular heartbeat
- Joint pain
- Nausea
|
GHK-Cu |
HairImmune systemLongevitySkin |
- Enhances skin elasticity
- Reduces fine lines and wrinkles
- Reverses thinning of aging skin
- Prevents aging through its antioxidant effects
- Accelerates wound healing
- Improves lung health
- Fights hair loss
- Accelerates nerve regeneration
- Fights anxiety
- Combats cognitive dysfunction
- Fights inflammation
|
- SQ: 1-2 mg daily for 6 weeks, can be split in half for morning/day. Follow by at least 4 weeks off. Can repeat the cycle 3-4 times a year
- Topical: 1-2 pumps daily for 30 days (5% concentration)
|
Approximately 30 minutes (when applied topically; systemic half-life can vary but is typically short) |
BPC-157 (often paired for enhanced wound healing and anti-inflammatory effects) |
Avoid combining with strong antioxidants (like high-dose Vitamin C) directly in the same application, as it may reduce GHK-Cu's effectiveness. |
|
- Copper allergy (careful!)
- If anything more than mild local ISR - discontinue the use of the peptide
- Dizziness
- Fatigue
- Headache
- Increased appetite
- Increased blood pressure
- Nausea
- Sun sensitivity
- The lunula of the nail can turn blue (will revert to normal in a few weeks)
|
Ipamorelin |
Anti-AgingImmune systemLongevityMusclesSleepWeight Loss |
- Increased cellular repair and regeneration
- Collagen production
- Improve lean muscle mass
- Decrease body fat
- Improve sleep
- Improve bone density
- Anti-aging and improve overall well-being
|
- Treatment length: no longer than 8 weeks, with equal time off
- SQ: 200 mcg nightly (5 nights on, 2 nights off)
- Ipamorelin is often stacked with CJC-1295 no DAC: SQ 200mcg/200mcg nightly (5 nights on, 2 nights off) Wait 2-3 hours after eating, and don’t eat for another 30 minutes after injection
- Ipamorelin is often stacked with Tesamorelin: SQ: 1 mg tesamorelin right before bed (at least 90 minutes after food) and 200 mcg ipamorelin in the morning
|
2 hours |
CJC-1295, Tesamorelin |
Avoid combining with other GHRPs (growth hormone-releasing peptides) in excess, as it may lead to overstimulation and increased side effects. |
- Human growth hormone releasing peptide (GHRP)
- GHRP should be paired with GHRH (e.g., Tesamorelin or CJC-1295), as it increases the GHRH effect and you can use a lower dose
|
- Facial flushing
- Feeling warm
- Tachycardia (rare, usually short-lived 5 minutes)
- ISR
- Headaches
- Muscle pain
- Water retention
|
KPV |
HealingSkin |
- Anti-inflammatory, metaflammation
- Immune modulation
- Gastrointestinal repair: IBS, ulcerative colitis, intestinal damage, colon cancer
- Wound healing
- Injury healing
- Skin appearance (repairs skin barrier proteins)
- Helps with psoriasis and eczema
|
- Oral: 500 mcg capsule twice a day
- SQ: 200-400 mcg daily
- Topical: KPV (2 mg/g) + D3 (1000 iu/g) topical cream (30 ml TopiClick): 0.5 ml applied to area twice daily
|
2 hours |
Vitamin D3 |
Avoid combining with strong immunosuppressants, as it may counteract KPV's immune-modulating effects. |
KPV is known for its anti-inflammatory and gut-repair benefits and is used both orally and topically. It can be especially beneficial for inflammatory skin conditions and gastrointestinal issues. |
- Diarrhea
- Headache
- Nausea
- Vomiting
|
MOTS-C |
EnergyLongevityMitochondrialWeight Loss |
- Significantly decreases the fat accumulation in the liver
- Improves cardiovascular health
- Fights bone loss
- Increases life expectancy
- Fights bacterial infection
- Delays the progression of atherosclerosis, Alzheimer's and chemotherapy-induced side-effects
- Supports glucose/insulin regulation
- Weight management by increasing energy expenditure
- Improves exercise tolerance
- Prevents macular eye degeneration
|
- Treatment length: 4-6 weeks
- SQ: 5 mg three times a week for 4-6 weeks
|
2-3 hours |
SS-31 (often cycled after SS-31 as indicated, for mitochondrial support and anti-aging benefits) |
Not recommended to combine with insulin or other glucose-lowering agents without medical supervision, as MOTS-C affects insulin sensitivity and glucose regulation. |
|
- Fluid retention
- High blood sugar
- Stomach upset
|
NAD+ |
Cognitive functionImmune systemLongevityMusclesWeight Loss |
- Produces anti-aging benefits
- Increases energy levels
- Weight loss
- Increases muscle mass and strength
- Improves cognitive function
- Improves cardiovascular, liver, kidney health
- Lowers blood pressure
- Boosts immune function
|
- SQ: Mix with 3ml BAC; do first thing in AM:
- 1-2 week: 25 mg twice a week
- 3-4 week: 50 mg twice a week
- 5-6 week: 100 mg twice a week
- 7+ weeks: 100 mg up to 3x a week
|
2-4 hours |
Resveratrol, Quercetin (often combined to enhance anti-aging and cellular repair effects) |
Blood thinners or anticoagulants (due to potential impact on blood clotting); also, avoid with medications or conditions affecting heart, liver, or kidney health without medical supervision |
- Nicotinamide Adenine Dinucleotide
- Not recommended for individuals with heart disease, kidney disease, or liver disease. Also individuals on blood thinners or meds that affect blood clotting should not use NAD+.
|
- Decreased blood levels of phosphorus
- Decreased insulin sensitivity
- Decreased platelets
- Dizziness
- Frontal dull headaches
- Nausea
- Heart palpitations
- Shortness of breath
- Constipation
- Increased plasma bilirubin, decreased levels of gamma glutamyl transferase, lactate dehydrogenase, and aspartate aminotransferase
|
Retatrutide |
Weight LossMetabolic Health |
- Promotes significant weight loss through appetite suppression and increased energy expenditure
- Improves blood sugar control, beneficial for individuals with type 2 diabetes or pre-diabetes
- Reduces liver fat and supports cardiovascular health
- Enhances metabolic health and supports long-term weight management
|
- Clinical Trial Dosing Protocol:
- Weeks 1–4: 2 mg once weekly
- Weeks 5–8: 4 mg once weekly
- Weeks 9–12: 8 mg once weekly
- Weeks 13 onward: 12 mg once weekly
- This gradual dose escalation aimed to enhance tolerability and minimize potential side effects.
|
Approximately 5-7 days |
AOD-9604 |
Avoid combining with other GLP-1 receptor agonists or investigational weight-loss drugs to prevent overstimulation and side effects. |
Retatrutide is currently investigational and not approved for clinical use. Any use should be within clinical trials or under the supervision of healthcare professionals. Gradual dose escalation is key to improving tolerability and achieving optimal outcomes.
|
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Gastrointestinal symptoms, typically mild to moderate in severity
|
Selank |
Cognitive functionImmune systemMood |
- Anti-anxiety
- Improves cognitive function
- Boosts immune function
- Treats alcohol withdrawal symptoms
- Improves liver health
|
- Intranasal: 750-1000 mcg daily in the morning (SD)
- SQ: 100-300 mcg daily in the morning (SD)
|
Approximately 2-4 hours |
Semax |
Not recommended with other strong sedatives or CNS depressants, as effects may overlap or intensify. |
Can be used as an antidepressant, anxiolytic, generalized anxiety disorder (GAD) treatment |
- Dizziness
- Fatigue
- Hair loss
- Headaches
- Nasal irritations
- Nausea
- Sore throat
|
Semaglutide |
Weight LossType 2 Diabetes |
- Promotes weight loss by reducing appetite and calorie intake
- Improves blood sugar control and insulin sensitivity
- May lower cardiovascular risk in individuals with obesity or diabetes
- Supports long-term weight maintenance
- Reduces liver fat, which can benefit individuals with fatty liver disease
|
- For Weight Management:
- Starting Dose: 0.25 mg once weekly for 4 weeks
- Increase to 0.5 mg once weekly for 4 weeks
- Increase to 1 mg once weekly for 4 weeks
- Continue increasing every 4 weeks:
- 1.7 mg once weekly
- Final maintenance dose: 2.4 mg once weekly
- For Type 2 Diabetes (Ozempic):
- Starting Dose: 0.25 mg once weekly for 4 weeks (not therapeutic but minimizes side effects)
- Increase to 0.5 mg once weekly
- If additional glycemic control is needed, increase to 1 mg once weekly after at least 4 weeks
- Maximum dose: 2 mg once weekly (if needed)
|
Approximately 7 days |
AOD-9604 |
Avoid combining with other GLP-1 agonists (e.g., Liraglutide, Tirzepatide) to prevent excessive GLP-1 receptor stimulation |
Semaglutide is a GLP-1 receptor agonist primarily used for weight loss and blood glucose control. Doses should be increased gradually to minimize side effects.
|
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Fatigue
- Risk of hypoglycemia when combined with other blood sugar-lowering agents
|
Semax |
Cognitive functionMood |
- Improves heart health
- Boosts immunity
- Accelerates wound healing
- Improves brain health and performance (memory, attention, and learning capacity)
- Lowers the risk of stroke
- Improves mood
|
- Intranasal: 750-1000 mcg daily in the morning
- SQ: 100-300 mcg daily in the morning
|
Approximately 3-4 hours |
Selank |
Not recommended with strong stimulants or antidepressants without medical supervision, as interactions could impact mood or cognition. |
Nootropic peptide |
- Higher doses can lead to desensitization
- Hair loss
- Discoloration of the nasal cavity
- Increase in blood sugar levels of diabetic patients
|
TB-500 |
HealingLongevity |
- Healing and tissue repair
- Muscle atrophy treatment
- Cardiovascular disease treatment
- Provides pain relief
- Possesses strong anti-inflammatory properties
- Reducing consequences of aging and viral infection
|
- SQ: 750 mcg daily for 20 days
|
1-2 days |
BPC-157, Thymosin Alpha-1 |
Avoid combining with strong immunosuppressants, as it may counteract its immunomodulating and healing benefits. |
- Frag 17-23
- TB-500 is the active region of Thymosin Beta-4, but some call TB-500 Thymosin Beta-4 as well
|
- Temporary tiredness
- Headache
- Possible dizziness
- Mild injection site irritation
- Rarely, flushing or increased heart rate
|
Tesamorelin |
BonesFocusMusclesSleepWeight Loss |
- Reduces triglycerides, liver, and visceral fat
- Decreases middle fat
- Improves bone mineral density
- Supports muscle metabolism
- Benefits cardiovascular health
- Can improve cognitive function
- Depending on the needs, may be better than CJC-1295
|
- Treatment length: 3 - 6 months with 1 month break
- Wait 2-3 hours after eating, and don’t eat for another 30 minutes after injection
- SQ: 1 mg 5-6 days a week before bed
- Tesamorelin is often stacked with Ipamorelin:
- SQ: 1 mg tesamorelin right before bed (at least 90 minutes after food) and 200 mcg ipamorelin in the morning
|
30 minutes |
Ipamorelin |
CJC-1295 |
- Human growth hormone-releasing hormone (GHRH). GHRH should be paired with GHRP, as it increases the GHRP effect and you can use a lower dose
- Brand name - EGRIFTA
- Developed to treat HIV lipodystrophy
|
- ISR
- Difficulty breathing
- Dizziness
- Elevations in blood sugar levels
- Fast heartbeat
- Hives
- Joint pain
- Night sweats
- Numbness
- Rash
- Vomiting
|
Thymosin Alpha-1 |
Immune system |
- Eradicates bacteria, viruses, and fungi
- Boosts immune system
- Suppresses cancer and tumor growth
- Accelerates the wound healing process
- Fights inflammation
- Increases vaccine effectiveness
|
- SQ: 450 mcg daily for 30 days (GDP)
- 90 mcg daily for 1 month (for a total of 5 mg) (CCMT)
- 1.5 mg every third day for two weeks for viral infection or up to three months for HIV, cancer, Hepatitis B/C, or complicated immune suppression (SD)
|
2 hours |
Thymosin Beta-4, TB-500 |
|
- FDA approved
- Some physicians are using thymosin for chronic fatigue, Lyme disease, autoimmune function
|
- Fatigue
- Fever
- Low white blood cells
- Muscle aches
- Nausea
- Vomiting
|
Tirzepatide |
Weight LossType 2 Diabetes |
- Significant weight loss by reducing appetite and food intake
- Improves blood sugar control and insulin sensitivity
- Reduces cardiovascular risk factors in individuals with obesity or type 2 diabetes
- Supports metabolic health and helps prevent further weight gain
|
- Starting Dose:
- 2.5 mg once weekly for 4 weeks (primarily to reduce side effects)
- Titration Schedule:
- Increase to 5 mg once weekly for at least 4 weeks
- If additional effect is needed, further increase as follows:
- 7.5 mg once weekly for 4 weeks
- 10 mg once weekly for 4 weeks
- 12.5 mg once weekly for 4 weeks
- Maximum dose: 15 mg once weekly
- Maintenance Dose:
- The effective maintenance dose is individualized, but 10 mg to 15 mg once weekly is common for most individuals
|
Approximately 5-7 days |
AOD-9604 |
Avoid combining with other GLP-1 or GIP agonists (such as Semaglutide) to prevent overstimulation and reduce side effects |
Tirzepatide is a dual GIP and GLP-1 receptor agonist, effective for weight management and blood sugar control. Doses should be increased gradually to minimize gastrointestinal side effects.
|
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Fatigue
- Risk of hypoglycemia, especially when used with other glucose-lowering medications
|
L-Glutathione |
AntioxidantDetoxification |
- Powerful antioxidant that reduces oxidative stress
- Supports liver detoxification and overall liver health
- Enhances immune function
- Improves skin health and reduces pigmentation
- Supports cellular repair and regeneration
- Protects against free radical damage
|
- SQ/IM: 200-600 mg weekly (for systemic antioxidant support)
|
Approximately 30 minutes to 1 hour (though effects can last longer due to its impact on cellular redox balance) |
Vitamin C, NAC (N-Acetylcysteine) |
Avoid with alcohol or acetaminophen, as these substances can increase liver load and deplete glutathione levels. |
L-Glutathione is one of the body's most important antioxidants and plays a critical role in detoxification, especially in the liver. It is also commonly used in skin-lightening regimens, although effects vary by individual. |
- Mild digestive upset (if taken orally in large doses)
- Allergic reactions in rare cases (rash or itching)
- Potential for low zinc levels with long-term high doses
- In some cases, dizziness or bloating may occur with IV administration
|
Cagrisema |
Weight LossMetabolic Health |
- Promotes weight loss through appetite suppression and increased energy expenditure
- Improves blood sugar control, beneficial for individuals with type 2 diabetes
- Enhances insulin sensitivity and supports metabolic health
- Reduces liver fat, aiding individuals with fatty liver disease
- Supports cardiovascular health by improving metabolic markers
|
- SQ: Start with 0.5 mg once weekly
- Gradually increase to 2.4 mg once weekly over a few weeks as tolerated
|
Approximately 6-7 days, allowing for once-weekly dosing |
AOD-9604 |
Avoid combining with other GLP-1 receptor agonists (such as Semaglutide or Tirzepatide) to prevent overstimulation of GLP-1 receptors and reduce side effects. |
Cagrisema is a combination of cagrilintide (an amylin analog) and semaglutide (a GLP-1 agonist), designed to synergistically promote weight loss and improve metabolic health. It is currently under investigation and may become a potent option for weight management. |
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Injection site reactions
- Fatigue
- Risk of hypoglycemia when combined with other blood sugar-lowering agents
|
Melanotan 2 (MT2) |
TanningSkin Health |
- Stimulates melanin production, leading to a natural tan without UV exposure
- May protect skin from UV damage by enhancing pigmentation
- Reduces risk of sunburn for individuals with fair skin
- Increases libido as an unexpected side effect for some users
- May provide mild appetite suppression
|
- SQ: Start with a small test dose of 0.25 mg to assess tolerance
- Gradually increase to 0.5-1 mg per day until desired pigmentation is achieved
- Maintenance dose: 0.5 mg 1-2 times per week to sustain tan
|
30-60 minutes |
Moderate sun exposure (enhances tanning effects; however, caution with UV exposure is advised) |
Avoid excessive UV exposure or tanning beds, as th
|
PT-141 |
Sexual HealthLibido Enhancement |
- Enhances libido and sexual arousal in both men and women
- Used to treat sexual dysfunction, including erectile dysfunction in men and hypoactive sexual desire disorder (HSDD) in women
- May improve overall mood and reduce anxiety related to sexual performance
|
- SQ: Typical dose is 1.25 mg administered subcutaneously about 45 minutes before anticipated sexual activity
- Not recommended to use more than once every 24-48 hours
|
2-3 hours |
Can be combined cautiously with lifestyle practices that reduce stress or anxiety (e.g., meditation, relaxation techniques) to further improve mood and performance. |
Avoid alcohol in excess, as it may reduce the effectiveness of PT-141 and increase side effects such as nausea. |
PT-141 works by activating melanocortin receptors involved in sexual arousal rather than through the vascular system like traditional ED medications, making it unique for sexual health. |
- Nausea (one of the most common side effects)
- Flushing
- Headache
- Increased blood pressure (should be used cautiously in individuals with hypertension)
- Dizziness
- Injection site reactions
|
Gonadorelin |
Hormone RegulationFertility |
- Stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), supporting testosterone production in men and estrogen production in women
- Used to diagnose and treat hypothalamic-pituitary-gonadal (HPG) axis issues
- May help restore natural testosterone levels in men with low levels due to HPG axis dysfunction
- Supports reproductive health and fertility in both men and women
|
- SQ: 100-200 mcg administered 1-3 times daily
|
10-20 minutes |
hCG (human chorionic gonadotropin) |
Avoid combining with other hormone-modulating drugs without medical supervision, as it may disrupt the balance of the HPG axis. |
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH) and is primarily used in clinical settings to assess pituitary function or stimulate natural hormone production in cases of deficiency. |
- Headache
- Abdominal discomfort
- Nausea
- Flushing
- Injection site reactions
- Possible changes in mood due to hormone fluctuations
|
TB-500 + BPC-157 |
HealingInjury RecoveryAnti-Inflammatory |
- Accelerates wound healing and tissue repair, particularly effective for muscle, ligament, and tendon injuries
- Reduces inflammation and provides pain relief, making it beneficial for chronic injuries or inflammatory conditions
- Enhances recovery time post-surgery or injury
- Supports cardiovascular health and may improve blood flow to injured areas
- Promotes cellular repair and regeneration, aiding in overall musculoskeletal health
|
- SQ: TB-500: Start with 2-2.5 mg twice weekly for the first 4-6 weeks (loading phase). After this, reduce to a maintenance dose of 2-2.5 mg once weekly.
- SQ: BPC-157: Use 250-500 mcg daily, split into two doses (morning and evening). BPC-157 is typically taken continuously until desired healing or improvement is achieved.
- Protocol Duration: Use both peptides together for 4-6 weeks for acute injuries, followed by a maintenance dose if necessary.
|
- TB-500: 1-2 days
- BPC-157: Approximately 4 hours
|
Vitamin C, Collagen supplements |
Avoid combining with strong immunosuppressants, as this could reduce the healing effects of both peptides. |
BPC-157 can be injected closer to the injury site, while TB-500 is typically injected subcutaneously without a need for localization. |
- Mild headache
- Temporary tiredness or lethargy
- Injection site irritation
- Nausea (rare)
- Possible mild dizziness
|
Tesamorelin + Retatrutide |
Weight LossMetabolic HealthAnti-Aging |
- Promotes significant weight loss by reducing appetite and increasing energy expenditure
- Enhances fat loss, particularly visceral fat reduction, making it beneficial for individuals with obesity or metabolic syndrome
- Supports muscle preservation during weight loss, which is particularly helpful for those aiming to retain lean muscle mass
- Improves insulin sensitivity and helps regulate blood glucose levels, beneficial for those with type 2 diabetes or insulin resistance
- Supports cardiovascular health by reducing body fat and improving metabolic markers
|
- SQ: Tesamorelin: Administer 1-2 mg daily, typically in the morning. Dosage can be adjusted based on individual response and medical guidance.
- SQ: Retatrutide: Start with 2.5 mg once weekly for the first 4 weeks. Increase to 5 mg once weekly for an additional 4 weeks, then adjust up to a maintenance dose of 10 mg once weekly if tolerated.
- This combination is often used for a period of 12-24 weeks, or as recommended by a healthcare provider.
|
- Tesamorelin: Approximately 26-38 minutes
- Retatrutide: Approximately 5-7 days, allowing for once-weekly dosing
|
AOD-9604, Vitamin D |
GLP-1 |
The combination is particularly effective for those with stubborn visceral fat or metabolic syndrome. However, close monitoring of blood sugar levels is recommended, especially in individuals with diabetes. When used with AAS, it is advisable to monitor lipid profiles regularly. |
- Tesamorelin: Injection site reactions, mild joint pain, increased appetite, nausea, occasional flushing
- Retatrutide: Nausea, vomiting, diarrhea, constipation, fatigue, possible hypoglycemia when combined with other glucose-lowering medications
|
CJC-1295 + Semaglutide |
Weight LossAnti-AgingMetabolic Health |
- Supports weight loss by reducing appetite and promoting fat metabolism
- Enhances growth hormone (GH) secretion, aiding in muscle preservation and fat loss
- Improves insulin sensitivity and helps regulate blood sugar levels, beneficial for those with type 2 diabetes or insulin resistance
- Supports skin health, tissue repair, and anti-aging due to increased GH levels
- Promotes cardiovascular health by improving metabolic markers and reducing body fat
|
- SQ: CJC-1295: Administer 100 mcg daily or 2-3 times per week if using CJC-1295 with DAC (long-acting form), or 100-200 mcg daily if using without DAC. Typically injected in the morning or before sleep.
- SQ: Semaglutide: Start with 0.25 mg once weekly for 4 weeks to assess tolerance. Increase to 0.5 mg once weekly for 4 additional weeks, then to a maintenance dose of 1.0 mg once weekly as needed.
- Protocol Duration: This combination is often used for 12-24 weeks.
|
- CJC-1295 with DAC: Approximately 6-8 days, allowing for weekly dosing
- CJC-1295 without DAC: Approximately 30 minutes, requiring more frequent dosing
- Semaglutide: Approximately 7 days, allowing for once-weekly dosing
|
AOD-9604, BPC-157 |
Avoid combining with other GLP-1 receptor agonists (such as Tirzepatide) to prevent overstimulation of GLP-1 receptors and excessive side effects. |
CJC-1295 when used with DAC is a long-acting growth hormone-releasing hormone (GHRH) analog that supports the body’s natural production of GH. Combined with Semaglutide, a GLP-1 receptor agonist, this pairing is effective for individuals aiming for fat loss while preserving muscle mass and improving metabolic health. Gradual dose escalation with Semaglutide is recommended to minimize gastrointestinal side effects. |
- CJC-1295: Injection site reactions, mild water retention, headache, potential fatigue
- Semaglutide: Nausea, vomiting, diarrhea, constipation, fatigue, potential hypoglycemia when combined with other glucose-lowering medications
|
Semax + Selank |
Cognitive EnhancementMood SupportAnxiety Reduction |
- Improves cognitive function, including memory, attention, and learning capacity
- Reduces anxiety and promotes a sense of calm without sedation
- Enhances focus and mental clarity, particularly beneficial for tasks requiring sustained attention
- Boosts immune function and may support overall brain health
- Provides neuroprotective effects, potentially protecting against neurodegenerative conditions
|
- Semax: 500-1000 mcg daily, typically administered in the morning. This can be split into two doses if needed.
- Selank: 750-1000 mcg daily, typically administered in the morning. Can also be split into two doses for sustained effects throughout the day.
- Protocol Duration: Use for 4-8 weeks, with periodic breaks if used long-term to prevent receptor desensitization.
|
- Semax: Approximately 3-4 hours
- Selank: Approximately 2-4 hours
|
None required |
Avoid combining with strong sedatives or other anxiolytics, as it may alter the effects or lead to overstimulation. |
Both peptides work synergistically when combined, enhancing mood and cognitive benefits without the need for additional supplements. |
- Mild headache
- Nasal irritation (due to intranasal administration)
- Rarely, dizziness or mild nausea
- Potential for receptor desensitization with prolonged use (recommended to cycle use if using long-term)
|
TB-500 + GHK-Cu + BPC-157 |
HealingAnti-InflammatorySkin & Tissue Repair |
- Accelerates tissue repair, wound healing, and recovery from injuries, particularly effective for muscle, tendon, and ligament healing
- Reduces inflammation, providing relief for both acute and chronic injuries
- Supports skin health and may improve skin elasticity, tone, and texture due to GHK-Cu's skin-regenerating properties
- Promotes collagen synthesis and cellular repair, benefiting joints and connective tissues
- May improve blood flow to damaged tissues, enhancing overall healing outcomes
|
- SQ: TB-500: Start with 2 mg twice weekly for 4-6 weeks (loading phase), then reduce to a maintenance dose of 2 mg once weekly.
- GHK-Cu: 100-200 mcg daily, either injected subcutaneously or applied topically for localized skin benefits.
- BPC-157: 250-500 mcg daily, split into two doses (morning and evening), injected subcutaneously near the injury site if needed.
- Protocol Duration: Combine for 4-8 weeks, especially during injury recovery, with periodic breaks if used long-term.
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- TB-500: Approximately 1-2 days
- GHK-Cu: Approximately 30 minutes (topical effects last longer)
- BPC-157: Approximately 4 hours
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Vitamin C (supports collagen synthesis), collagen supplements |
Avoid combining with strong immunosuppressants, as these may counteract the healing and immune-supportive effects of this combination. |
This combination is popular among athletes and individuals recovering from injury or surgery, due to its synergistic effects on healing and inflammation reduction. |
- Mild headache
- Temporary tiredness or lethargy
- Injection site irritation
- Nausea (rare)
- Possible mild dizziness with initial doses
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NAD+ + L-Glutathione |
Cellular HealthDetoxificationAnti-Aging |
- Boosts cellular energy production and supports mitochondrial health, aiding in overall energy and stamina
- Provides potent antioxidant effects, reducing oxidative stress and protecting cells from damage
- Enhances detoxification processes, particularly supporting liver health and overall detoxification pathways
- Supports cognitive function and may improve focus, memory, and mental clarity
- Aids in skin health by protecting against cellular damage and promoting regeneration
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- SQ: NAD+: 250-500 mg once weekly or biweekly, depending on individual needs and tolerance
- L-Glutathione: 600-1200 mg, administered immediately following the NAD+ infusion to support detoxification and antioxidant effects
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- NAD+: 2-4 hours
- L-Glutathione: 30 minutes to 1 hour
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Vitamin C, CoQ10, Alpha-Lipoic Acid (ALA) |
Avoid combining with alcohol and acetaminophen |
This combination is popular for those seeking enhanced energy, cognitive support, and antioxidant protection, and it is often used in longevity and detoxification protocols. |
- Mild digestive upset (with oral L-Glutathione)
- Possible flushing or warmth during IV infusion
- Mild headache or fatigue (common with NAD+ infusions initially)
- Rare allergic reactions (such as rash or itching)
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Semaglutide + CJC-1295/Ipamorelin Blend |
Weight LossLongevityMusclesCognitive Function |
- Semaglutide:
- Significant weight loss through appetite suppression and reduced food cravings
- Improved blood sugar regulation
- Lowered risk of cardiovascular disease
- CJC-1295/Ipamorelin Blend:
- Boosts growth hormone levels, improving muscle growth and recovery
- Enhances fat metabolism for weight loss
- Improves sleep quality and recovery
- Supports anti-aging benefits, including skin and collagen health
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- Semaglutide: SQ: Start with 0.25 mg weekly, gradually increasing to 1-2.4 mg weekly depending on tolerance and weight loss goals. Administer on an empty stomach.
- CJC-1295/Ipamorelin Blend: (3 - 6 months with 1 month break)
- SQ: 200-300 mcg daily (5 nights on, 2 nights off) or 300 mcg three times per week, depending on dosing preferences. Inject before bed for best results.
- Optionally stack with Tesamorelin (1 mg before bed) to further enhance growth hormone secretion.
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- Semaglutide: ~7 days
- CJC-1295: ~6-8 days (long-acting)
- Ipamorelin: ~2 hours
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Tesamorelin, low-carb/ketogenic diet for synergistic effects on fat loss |
Other glucose-lowering medications (risk of hypoglycemia), high doses of GH peptides without proper monitoring |
- Semaglutide: Monitor blood sugar levels regularly, especially for individuals with diabetes or pre-diabetes. Start with a low dose to minimize side effects like nausea.
- CJC-1295/Ipamorelin Blend: Take on an empty stomach to maximize effects, avoiding food for 2-3 hours before and 30 minutes after injection.
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- Semaglutide: Nausea, vomiting, or diarrhea (common during dose escalation), fatigue or mild dizziness, rare cases of pancreatitis or gallbladder issues
- CJC-1295/Ipamorelin Blend: Mild flushing, headaches, or water retention, short-lived injection site irritation
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SS-31 |
EnergyMitochondria |
- Improves mitochondrial function
- Reduces oxidative stress
- Protects against age-related degeneration
- Enhances cardiovascular and skeletal muscle performance
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- Treatment length: 2-4 weeks, may be extended for chronic conditions
- SQ: 2 mg/kg body weight daily
- IV: Clinical supervision recommended for severe cases
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4 hours |
GHK-Cu, Thymosin Beta-4 |
N/A |
SS-31 is a mitochondrial-targeting peptide that binds to cardiolipin, a component of the inner mitochondrial membrane, to enhance bioenergetics. |
- Injection site redness
- Rare systemic side effects include nausea, dizziness, or headache
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