Last updated: May 18, 2026
List prices (US, 2026)
| Drug | Brand | Monthly list |
|---|---|---|
| Semaglutide | Wegovy | ~$1,349 |
| Semaglutide | Ozempic | ~$968-1,200 |
| Semaglutide oral | Rybelsus | ~$1,000 |
| Tirzepatide | Zepbound | ~$1,059 |
| Tirzepatide | Mounjaro | ~$1,069 |
| Liraglutide | Saxenda | ~$1,400 |
Manufacturer self-pay programs
LillyDirect (Zepbound)
Self-pay program for Zepbound vials (not pens): 2.5mg ~$399/month, 5mg ~$549/month, 7.5mg ~$599/month, 10-15mg ~$649/month.
Novo Nordisk savings cards
Wegovy and Ozempic offer manufacturer copay assistance for commercially insured patients (typically reduces copay to $0-25 per month, capped annually).
Insurance coverage patterns
- Commercial insurance: Variable. Obesity drugs (Wegovy, Zepbound, Saxenda) often excluded. T2D drugs (Ozempic, Mounjaro) typically covered for diabetes diagnosis.
- Medicare: Federal law prevents Part D from covering obesity drugs. Diabetes use is covered.
- Medicaid: State-by-state variability for obesity coverage.
- Employer-sponsored plans: Growing trend toward obesity coverage as part of employee wellness initiatives.
Compounded GLP-1 status (2026)
The FDA declared the semaglutide and tirzepatide shortages resolved in early 2025, narrowing the legal basis for compounding. Many state pharmacy boards have since restricted compounded GLP-1 sales. Telehealth services that previously offered compounded semaglutide/tirzepatide have largely transitioned to other models or shut down.
Is there a generic semaglutide or tirzepatide?<br />
No FDA-approved generics. Patent protection extends through ~2032 for semaglutide and longer for tirzepatide.
Why is Ozempic cheaper than Wegovy if they’re the same drug?<br />
Pricing reflects indication and competitive context. Wegovy targets the obesity market with less price competition. Ozempic competes against multiple T2D drugs.
Will GLP-1 prices drop?<br />
Continued competition and possible regulatory action may pressure prices. Several Phase 3 candidates (retatrutide, orforglipron) approaching approval will increase competition.
Are international GLP-1 prices different?<br />
Yes — substantially. EU and Canada prices are typically 40-70% of US list prices.